Multiphysics

Case study

Infant Incubator Thermal Modeling
The main environmental factor affecting a premature neonate is thermo-neutrality, as the baby is incapable of regulating and maintaining his/her body temperature at a constant level. Veryst developed a computational model of heat transfer inside an infant incubator to optimize its design.
Laminar Static Mixer Analysis
Laminar static mixers are often employed in industrial environments when the mixing of two or more fluids is required. However, their performance is impossible to analyze with a pure CFD approach. Veryst, in collaboration with Nordson EFD, developed a unique computational modeling tool to evaluate and optimize the design of such mixers.
LED Light Bulb Heat Transfer Simulation
Both the efficiency and life of an LED bulb drop when operated at high temperature. Given the wide range of possible shapes and sizes of heat sinks, Veryst Engineering developed a rapid and effective tool to compare design alternatives and estimate LED temperatures.
Lipid Nanoparticle Self-assembly for mRNA Vaccine Production
Controlling the size of lipid nanoparticles (LNPs) in small-batch pharmaceutical processes is critical for delivery efficiency in mRNA vaccines, cancer therapies, and point-of-care diagnostics. In this case study, Veryst simulated solvent mixing and LNP self-assembly kinetics in a microfluidic mixer to predict the size distribution of LNPs across a range of process flow conditions.
Microfluidic Mixer Concentration Profile
Veryst developed a coupled CFD mass transfer model to predict a microfluidic mixer configuration appropriate for mixing pure and salt water channels.
Multiphysics Analysis of a MEMS Switch
The responses of a MEMS switch immersed in fluids differs from that in a vacuum. Veryst Engineering developed a coupled electrostatic-fluid-structure interaction model to investigate the switch response time, deformation, and energy dissipation.
Oxygen Transport and Cellular Uptake in a Microchannel
Oxygen transport is a key factor in the design of cell culture systems such as organs-on-a-chip, microphysiological systems, and bioreactors. In this case study, we use multiphysics simulation to analyze oxygen transport and cellular uptake in a model microchannel bioreactor.
Peristaltic Pump Fluid - Structure Interaction
The performance of peristaltic pumps is influenced by tube dimensions, tube material, rotary mechanism, and fluid properties. Veryst Engineering developed a strongly coupled fluid-structure interaction model that captures the deformation of the tube, rollers, and fluid, including contact.
Phononic Band Gap Analysis
The call for structures that can selectively block acoustic waves of certain frequencies is growing, but their design is often inhibited by the lack of appropriate simulation tools in commercial FEA packages. Veryst developed a COMSOL Multiphysics model for unit cell band gap simulations, enabling the design and optimization of phononic band gap structures with target band gap width and locations.
Reagent Dry-Down in a Microwell
Manufacturing medical diagnostic kits involves drying reagents to be reconstituted later, during use. For this project, Veryst simulated reagent dry-down of a small volume of liquid in a microwell to investigate the effect of process parameters including oven temperature and humidity.
RF Tissue Ablation Simulation
Radio frequency tissue ablation is a commonly used and minimally invasive tissue treatment procedure. Accurately modeling this kind of coupled multiphysics problem is often challenging. Veryst developed a COMSOL Multiphysics model accounting for heat transfer, electric field, and fluid flow to study the RF tissue ablation problem where an electrode is targeting a tissue close to a blood vessel.
Scaling Yield and Mixing in Chemical Reactors
Scaling chemical reactions from the lab to pilot or production requires a detailed understanding of the physical system, which frequently involves heat transfer, mass transfer, reaction kinetics, and fluid flow. This case study illustrates how multiphysics simulations can support design decisions involved in scaling up chemical reactors.
Sea Floor Energy Harvesting
Veryst Engineering developed proof-of-concept models for a device for harvesting energy from constant low speed ocean floor currents in order to power ocean sensors.
Simulating Compression Springs in a COMSOL Multiphysics Application
The design of compression springs is tied to their intended function and the acceptable levels of deformation and stress that the spring can withstand. Veryst designed and evaluated a standalone simulation application to capture important qualities, such as spring rate, natural frequencies, and estimated fatigue life, for both helical and conical compression springs.
Theoretical and Numerical Analysis of Low-Voltage Cascade Electroosmotic Pumps
Electroosmotic (EO) pumps are driven purely by electric fields and have no moving parts. Cascading EO pumps reduces voltage requirements. Veryst used computational fluid dynamics (CFD) and semi-analytical equivalent circuit theory to analyze the complex behavior of these pumps.

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